A new strategy for Cas protein recognition based on graph neural networks and SMILES encoding
Abstract The CRISPR-Cas system, an adaptive immune mechanism found in bacteria and archaea, has evolved into a promising genomic editing tool, with various types of Cas proteins playing a crucial role. In this study, we developed a set of strategies for mining and identifying Cas1 proteins. Firstly,...
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| Main Authors: | Gaoxiang Chen, Liya Hou, Zhanwei Li, Bin Xie, Yongqiang Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-99999-2 |
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