A new strategy for Cas protein recognition based on graph neural networks and SMILES encoding

Abstract The CRISPR-Cas system, an adaptive immune mechanism found in bacteria and archaea, has evolved into a promising genomic editing tool, with various types of Cas proteins playing a crucial role. In this study, we developed a set of strategies for mining and identifying Cas1 proteins. Firstly,...

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Bibliographic Details
Main Authors: Gaoxiang Chen, Liya Hou, Zhanwei Li, Bin Xie, Yongqiang Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-99999-2
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