Inducing cross-clade neutralizing antibodies against HIV-1 by immunofocusing.

<h4>Background</h4>Although vaccines are important in preventing viral infections by inducing neutralizing antibodies (nAbs), HIV-1 has proven to be a difficult target and escapes humoral immunity through various mechanisms. We sought to test whether HIV-1 Env mimics may serve as immunog...

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Bibliographic Details
Main Authors: Michael Humbert, Robert A Rasmussen, Helena Ong, Fabian M P Kaiser, Shiu-Lok Hu, Ruth M Ruprecht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003937&type=printable
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