Long-Term Follow-Up of a Glucocorticoid Minimizing Regimen for the Treatment of Severe Antineutrophil Cytoplasmic Autoantibody–Associated Vasculitis

Long-Term Follow-Up of a Glucocorticoid Minimizing Regimen for the Treatment of Severe Antineutrophil Cytoplasmic Autoantibody–Associated Vasculitis

Introduction: Glucocorticoids (GCs) are pivotal in treating antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV); however, their use is associated with significant toxicities. Findings of recent trials support reduced GC dosing, demonstrating efficacy with fewer adverse events....

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Main Authors: Stephen P. McAdoo, Ruth J. Pepper, Maria Prendecki, Amrita Dhutia, Tony Lopez, Aine Burns, Marie Condon, Sally Hamour, Megan Griffith, Jeremy Levy, Tom Cairns, Mark Little, Alan D. Salama, Charles D. Pusey
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Kidney International Reports
Subjects:
ANCA
cyclophosphamide
glomerulonephritis
rituximab
vasculitis
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925001378
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