Gut Microbiota Reshapes the Tumor Microenvironment and Affects the Efficacy of Colorectal Cancer Immunotherapy

Gut Microbiota Reshapes the Tumor Microenvironment and Affects the Efficacy of Colorectal Cancer Immunotherapy

ABSTRACT Background Colorectal cancer (CRC) is among the most prevalent malignant tumors in the digestive system and is the third leading cause of cancer‐related mortality. In recent years, immunotherapy has markedly enhanced the objective response and survival rates for CRC patients. However, the t...

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Main Authors: Fayuan Wang, Weidong Chen, Yingtian Jia, Tao He, Siyi Wu, Jiahui Xiang, Rui Chen, Qingfeng Jiang, Tengjiang Yu, Yong Lan, Wusheng Li, Liang Ma, Ping He, Shichao Li
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Cancer Medicine
Subjects:
colorectal cancer
gut microbiota
immune checkpoint inhibitors(ICIs)
immunotherapy
tumor microenvironment (TME)
Online Access:https://doi.org/10.1002/cam4.70994
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https://doi.org/10.1002/cam4.70994

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