Molecular counting enables accurate and precise quantification of methylated ctDNA for tumor-naive cancer therapy response monitoring

Molecular counting enables accurate and precise quantification of methylated ctDNA for tumor-naive cancer therapy response monitoring

Abstract Personalized cancer treatment can significantly extend survival and improve quality of life for many patients, but accurate and real-time therapy response monitoring remains challenging. To overcome logistical and technical challenges associated with therapy response monitoring via imaging...

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Main Authors: Patrick Peiyong Ye, Robb Viens, Katherine E Shelburne, Sydne Scot Langpap, Xavier S Bower, Jonathan Jiahui Shi, Wen Zhou, Jan Christian Wignall, Joyce Jiawei Zhu, Brian D. Woodward, Hatim Husain, David S. Tsao, Oguzhan Atay
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-90013-3
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https://doi.org/10.1038/s41598-025-90013-3

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