Human breast milk-derived exosomes attenuate lipopolysaccharide-induced activation in microglia

Abstract Microglia mediate the immune response in the central nervous system to many insults, including lipopolysaccharide (LPS), a bacterial endotoxin that initiates neuroinflammation in the neonatal population, especially preterm infants. The synthesis of the proinflammatory proteins CD40 and NLRP...

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Bibliographic Details
Main Authors: Oluwatomi Akinduro, Sanjay Kumar, Yuechuan Chen, Barbara Thomas, Quamarul Hassan, Brian Sims
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Neuroinflammation
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Online Access:https://doi.org/10.1186/s12974-025-03345-2
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