Physiological effects of bi-level high-flow nasal cannula in healthy individuals: a proof of concept trial

Physiological effects of bi-level high-flow nasal cannula in healthy individuals: a proof of concept trial

BackgroundHigh-flow nasal cannula (HFNC) delivers a continuous, unidirectional high flow of oxygen (Uniflow) throughout the respiratory cycle. Despite its positive pressure effects in the nasopharynx, the persistent high flow during expiration imposes additional work of breathing and disrupts the pa...

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Bibliographic Details
Main Authors: Jin Won Huh, Woo Jung Seo, Jee Hwan Ahn, Su Yeon Lee, Hee Jung Suh, Ga Jin Seo, Eun Young Kim, Min Kyung Jang, Chae-Man Lim
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Medicine
Subjects:
high flow nasal cannula
Biflow
respiratory cycle
pressure-time product
concept trial
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1538832/full
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https://www.frontiersin.org/articles/10.3389/fmed.2025.1538832/full

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