Alpha and Omega Classification of β-Lactamase/Transpeptidase-like Superfamily Proteins Based on the Comparison of Their Structural Catalytic Cores

Alpha and Omega Classification of β-Lactamase/Transpeptidase-like Superfamily Proteins Based on the Comparison of Their Structural Catalytic Cores

β-Lactamase/transpeptidase-like superfamily proteins are serine proteases that use the Ser–Lys catalytic dyad to carry out their biological functions. Here, we investigate the three known families of β-lactamase/transpeptidase-like superfamily proteins, β-lactamase/D-Ala carboxypeptidase, glutaminas...

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Bibliographic Details
Main Authors: Alexander I. Denesyuk, Konstantin Denessiouk, Mark S. Johnson, Vladimir N. Uversky
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
Subjects:
β-lactamase
DD-carboxypeptidase
glutaminase
3D structure
catalytic core
classification
Online Access:https://www.mdpi.com/1420-3049/30/9/2019
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