Therapeutic treatment of hepatitis E virus infection in pigs with a neutralizing monoclonal antibody

Therapeutic treatment of hepatitis E virus infection in pigs with a neutralizing monoclonal antibody

Abstract Hepatitis E virus (HEV) poses a significant risk to human health. In Europe, the majority of HEV infection are caused by the zoonotic genotype 3 (HEV-3), which can cause chronic hepatitis E in immunocompromised patients and those with pre-existing liver disease, and may eventually develop i...

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Bibliographic Details
Main Authors: Isabella Hrabal, Elmira Aliabadi, Sven Reiche, Saskia Weber, Cora M. Holicki, Laura Schmid, Christine Fast, Charlotte Schröder, Benjamin Gutjahr, Patrick Behrendt, Martin H. Groschup, Martin Eiden
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Hepatitis E virus
Therapy
Monoclonal antibody
In vitro characterization
Pig model
Online Access:https://doi.org/10.1038/s41598-025-95992-x
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https://doi.org/10.1038/s41598-025-95992-x

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