Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy

Purpose. To summarize the role of widefield optical coherence tomography angiography (WF-OCTA) in diabetic retinopathy (DR), extending from the acquisition strategies to the main clinical findings. Methods. A PubMed-based search was carried out using the terms “Diabetic retinopathy”, “optical cohere...

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Main Authors: Alessia Amato, Francesco Nadin, Federico Borghesan, Maria Vittoria Cicinelli, Irini Chatziralli, Saena Sadiq, Rukhsana Mirza, Francesco Bandello
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2020/8855709
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author Alessia Amato
Francesco Nadin
Federico Borghesan
Maria Vittoria Cicinelli
Irini Chatziralli
Saena Sadiq
Rukhsana Mirza
Francesco Bandello
author_facet Alessia Amato
Francesco Nadin
Federico Borghesan
Maria Vittoria Cicinelli
Irini Chatziralli
Saena Sadiq
Rukhsana Mirza
Francesco Bandello
author_sort Alessia Amato
collection DOAJ
description Purpose. To summarize the role of widefield optical coherence tomography angiography (WF-OCTA) in diabetic retinopathy (DR), extending from the acquisition strategies to the main clinical findings. Methods. A PubMed-based search was carried out using the terms “Diabetic retinopathy”, “optical coherence tomography angiography”, “widefield imaging”, and “ultra-widefield imaging”. All studies published in English up to August 2020 were reviewed. Results. WF-OCTA can be obtained with different approaches, offering advantages over traditional imaging in the study of nonperfusion areas (NPAs) and neovascularization (NV). Quantitative estimates and topographic distribution of NPA and NV are useful for treatment monitoring and artificial intelligence-based approaches. Curvature, segmentation, and motion artifacts should be assessed when using WF-OCTA. Conclusions. WF-OCTA harbors interesting potential in DR because of its noninvasiveness and capability of objective metrics of retinal vasculature. Further studies will facilitate the migration from traditional imaging to WF-OCTA in both the research and clinical practice fields.
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institution Kabale University
issn 2314-6745
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language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Journal of Diabetes Research
spelling doaj-art-644c38361f4346c991cfde5d6a8e4b5a2025-02-03T01:05:10ZengWileyJournal of Diabetes Research2314-67452314-67532020-01-01202010.1155/2020/88557098855709Widefield Optical Coherence Tomography Angiography in Diabetic RetinopathyAlessia Amato0Francesco Nadin1Federico Borghesan2Maria Vittoria Cicinelli3Irini Chatziralli4Saena Sadiq5Rukhsana Mirza6Francesco Bandello7Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, ItalyDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, ItalyDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, ItalyDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy2nd Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, GreeceDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USADepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USADepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, ItalyPurpose. To summarize the role of widefield optical coherence tomography angiography (WF-OCTA) in diabetic retinopathy (DR), extending from the acquisition strategies to the main clinical findings. Methods. A PubMed-based search was carried out using the terms “Diabetic retinopathy”, “optical coherence tomography angiography”, “widefield imaging”, and “ultra-widefield imaging”. All studies published in English up to August 2020 were reviewed. Results. WF-OCTA can be obtained with different approaches, offering advantages over traditional imaging in the study of nonperfusion areas (NPAs) and neovascularization (NV). Quantitative estimates and topographic distribution of NPA and NV are useful for treatment monitoring and artificial intelligence-based approaches. Curvature, segmentation, and motion artifacts should be assessed when using WF-OCTA. Conclusions. WF-OCTA harbors interesting potential in DR because of its noninvasiveness and capability of objective metrics of retinal vasculature. Further studies will facilitate the migration from traditional imaging to WF-OCTA in both the research and clinical practice fields.http://dx.doi.org/10.1155/2020/8855709
spellingShingle Alessia Amato
Francesco Nadin
Federico Borghesan
Maria Vittoria Cicinelli
Irini Chatziralli
Saena Sadiq
Rukhsana Mirza
Francesco Bandello
Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy
Journal of Diabetes Research
title Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy
title_full Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy
title_fullStr Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy
title_full_unstemmed Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy
title_short Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy
title_sort widefield optical coherence tomography angiography in diabetic retinopathy
url http://dx.doi.org/10.1155/2020/8855709
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