Single-centre, single-blind, randomized, active-controlled phase-3 non-inferiority study to investigate the safety and efficacy of the cardioplegic solution Cardioplexol™

Single-centre, single-blind, randomized, active-controlled phase-3 non-inferiority study to investigate the safety and efficacy of the cardioplegic solution Cardioplexol™

ObjectivesEffective and reliable cardioplegic cardiac arrest is crucial for maximizing myocardial protection and preserving postoperative contractile function. Aim of this study was to demonstrate, in line with an ongoing European registration procedure, the efficacy and safety of the new Cardioplex...

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Bibliographic Details
Main Authors: Hendrik T. Tevaearai Stahel, Gabriel Weiss, Peter Landowski, Sandra Folkmann, Marieluise Harrer, Bernard Voet, Martin Grabenwöger
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiac surgery
cardioplegic solution
cardioplegia
myocardial protection
extracorporeal circulation
randomized controlled trial
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1587713/full
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https://www.frontiersin.org/articles/10.3389/fcvm.2025.1587713/full

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