Effect of Ritanserin and Duloxetine on the Gene Expression of Primary Aniridia and Healthy Human Limbal Stromal Cells, In Vitro

Effect of Ritanserin and Duloxetine on the Gene Expression of Primary Aniridia and Healthy Human Limbal Stromal Cells, In Vitro

Abstract Introduction In congenital aniridia caused by mutations in paired box 6 (PAX6), PAX6 influences the migration and differentiation of limbal epithelial cells (LECs), thereby playing a pivotal role in aniridia-associated keratopathy. The antidepressants ritanserin and duloxetine affect PAX6 e...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhen Li, Nóra Szentmáry, Fabian N. Fries, Shweta Suiwal, Ning Chai, Berthold Seitz, Lei Shi, Maryam Amini, Tanja Stachon
Format: Article
Language:English
Published: Adis, Springer Healthcare 2024-09-01
Series:Ophthalmology and Therapy
Subjects:
Ritanserin
Duloxetine
PAX6
Limbal stromal cells
Limbal fibroblasts
Limbal keratocytes
Online Access:https://doi.org/10.1007/s40123-024-01032-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1007/s40123-024-01032-8

Similar Items