High-Fat-Diet-Induced Metabolic Disorders: An Original Cause for Neurovascular Uncoupling Through the Imbalance of Glutamatergic Pathways

High-Fat-Diet-Induced Metabolic Disorders: An Original Cause for Neurovascular Uncoupling Through the Imbalance of Glutamatergic Pathways

<b>Backgrounds/Objective:</b> The impact of metabolic disturbances induced by an unbalanced diet on cognitive decline in mid-life is now widely observed, although the mechanisms are not well identified. Here we report that glutamatergic vasoactive pathways are a key feature of high-fat-d...

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Bibliographic Details
Main Authors: Manon Haas, Maud Petrault, Patrick Gele, Thavarak Ouk, Vincent Berezowski, Olivier Petrault, Michèle Bastide
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
brain autoregulation
glutamate
metabolism
neurogliovascular coupling
nutrition
Online Access:https://www.mdpi.com/2227-9059/13/7/1712
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