Still not sterile: viability-based assessment of the skin microbiome following pre-surgical application of a broad-spectrum antiseptic reveals transient pathogen enrichment and long-term recovery

Still not sterile: viability-based assessment of the skin microbiome following pre-surgical application of a broad-spectrum antiseptic reveals transient pathogen enrichment and long-term recovery

ABSTRACT Broad-spectrum antiseptics such as chlorhexidine gluconate (CHG) have widespread use as pre-surgical tools to lower skin microbial burden and reduce the risk of surgical site infection. However, the short- and long-term effects of CHG on healthy skin microbial communities remain undefined d...

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Bibliographic Details
Main Authors: Elizabeth C. Townsend, Kayla Xu, Karinda De La Cruz, Lynda Huang, Shelby Sandstrom, Delanie Arend, Owen Gromek, John Scarborough, Anna Huttenlocher, Angela L. F. Gibson, Lindsay R. Kalan
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:Microbiology Spectrum
Subjects:
skin microbiome
antiseptic
viability PCR
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02873-24
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https://journals.asm.org/doi/10.1128/spectrum.02873-24

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