Sub-organellar mitochondrial hydrogen peroxide observed using a SNAP tag targeted coumarin-based fluorescent reporter

Sub-organellar mitochondrial hydrogen peroxide observed using a SNAP tag targeted coumarin-based fluorescent reporter

Mitochondria are major sites of reactive oxygen species (ROS) production within cells. ROS are important signalling molecules, but excessive production can cause cellular damage and dysfunction. It is therefore crucial to accurately determine when, how and where ROS are produced within mitochondria....

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Bibliographic Details
Main Authors: Ross Eaglesfield, Erika Fernandez-Vizarra, Erik Lacko, Stuart T. Caldwell, Nikki L. Sloan, Daniel Siciarz, Richard C. Hartley, Kostas Tokatlidis
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Redox Biology
Subjects:
Mitochondria
ROS
Self-labeling proteins
Redox signalling
Oxidative stress
Sub-cellular compartments
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725000151
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