Tumor microenvironment and cancer metastasis: molecular mechanisms and therapeutic implications

The tumor microenvironment (TME) plays a crucial role in cancer development and metastasis. This review summarizes the current research on how the TME promotes metastasis through molecular pathways, focusing on key components, such as cancer-associated fibroblasts, immune cells, endothelial cells, c...

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Bibliographic Details
Main Authors: Cigir Biray Avci, Bakiye Goker Bagca, Masoud Nikanfar, Leila Sabour Takanlou, Maryam Sabour Takanlou, Alireza Nourazarian
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1442888/full
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