Complement Proteins Identify Rapidly Progressive Diabetic Kidney Disease

Complement Proteins Identify Rapidly Progressive Diabetic Kidney Disease

Introduction: Mechanisms underlying diabetic kidney disease (DKD) progression remain incompletely understood. This study used untargeted and targeted mass spectrometry-based proteomics in 2 independent cohorts to capture rapidly progressive DKD. Methods: We conducted untargeted and targeted mass spe...

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Main Authors: Donghwan Yun, Sohyun Bae, Yuqian Gao, Lauren Lopez, Dohyun Han, Carrie D. Nicora, Tae Youn Kim, Kyung Chul Moon, Dong Ki Kim, Thomas L. Fillmore, Yon Su Kim, Avi Z. Rosenberg, Weijie Wang, Pinaki Sarder, Wei-Jun Qian, Maryam Afkarian, Seung Seok Han
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Kidney International Reports
Subjects:
biomarkers
complement system proteins
diabetic nephropathies
pathology
proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925002864
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