Backup in gene regulatory networks explains differences between binding and knockout results

Abstract The complementarity of gene expression and protein–DNA interaction data led to several successful models of biological systems. However, recent studies in multiple species raise doubts about the relationship between these two datasets. These studies show that the overwhelming majority of ge...

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Bibliographic Details
Main Authors: Anthony Gitter, Zehava Siegfried, Michael Klutstein, Oriol Fornes, Baldo Oliva, Itamar Simon, Ziv Bar‐Joseph
Format: Article
Language:English
Published: Springer Nature 2009-06-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.1038/msb.2009.33
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