Optimization of Fermentation Conditions for the Production of 2,3,5-Trimethylpyrazine by Recombinant <i>Bacillus licheniformis</i>

Optimization of Fermentation Conditions for the Production of 2,3,5-Trimethylpyrazine by Recombinant <i>Bacillus licheniformis</i>

2,3,5-Trimethylpyrazine (TMP) is an alkyl pyrazine with broad application prospects in the fields of food additives and medicine. L-threonine-3-dehydrogenase (TDH) is a key enzyme in the biosynthesis pathway of TMP. To explore the efficient and environmentally friendly production method of TMP, we c...

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Bibliographic Details
Main Authors: Xun Liu, Hongyi Gu, Handong Wang, Zhen Tang, Shuanglian Chen, Han Li, Wenli Quan
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Microorganisms
Subjects:
2,3,5-trimethylpyrazine
<i>Bacillus licheniformis</i>
<i>BlTDH</i> gene
recombinant strains
fermentation optimization
Online Access:https://www.mdpi.com/2076-2607/13/7/1477
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