Unraveling the role of UilS, a urea-induced acyl-homoserine lactonase that enhances Serratia marcescens fitness, interbacterial competition, and urinary tract infection

Unraveling the role of UilS, a urea-induced acyl-homoserine lactonase that enhances Serratia marcescens fitness, interbacterial competition, and urinary tract infection

ABSTRACT Serratia marcescens, a member of the Enterobacteriaceae family, is an opportunistic human pathogen and a frequent cause of urinary tract infections. Clinical isolates often exhibit resistance to multiple antibiotics, posing challenges for successful treatment. Understanding its pathogenic m...

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Main Authors: Marisel R. Tuttobene, Brayan S. Arango Gil, Gisela Di Venanzio, Javier F. Mariscotti, Rodrigo Sieira, Mario F. Feldman, María Soledad Ramirez, Eleonora García Véscovi
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mBio
Subjects:
Serratia marsescens
lactonase
quorum quenching
pathogenesis
bacterial virulence
Online Access:https://journals.asm.org/doi/10.1128/mbio.02505-24
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https://journals.asm.org/doi/10.1128/mbio.02505-24

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