Y chromosome variation and prostate cancer ancestral disparities

Y chromosome variation and prostate cancer ancestral disparities

Summary: Prostate cancer (PCa) is marked by significant ancestral bias, with African men disproportionately impacted. However, genome profiling studies have yet to explore the mutational landscape and disparity contribution of the male-determining Y chromosome. Using a cohort of 106 African and 57 E...

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Bibliographic Details
Main Authors: Pamela X.Y. Soh, Alice Adams, M.S. Riana Bornman, Jue Jiang, Phillip D. Stricker, Shingai B.A. Mutambirwa, Weerachai Jaratlerdsiri, Vanessa M. Hayes
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
Human genetics
Sequence analysis
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225006984
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