p53 upregulation is a frequent response to deficiency of cell-essential genes.

<h4>Background</h4>The role of p53 in the prevention of development of embryos damaged by genotoxic factors is well recognized. However, whether p53 plays an analogous role in preventing birth defects from genetic mutations remains an unanswered question. Genetic screens for mutations af...

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Bibliographic Details
Main Authors: Nadia Danilova, Asako Kumagai, Jenny Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015938&type=printable
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