Determination of a novel anticonvulsant drug GIZh-290 in rat plasma by liquid chromatography–tandem mass spectrometry

GIZh-290 is a new derivative of 4-phenylpyrrolidone, based on the structures of racetams that combine anticonvulsant and nootropic effects. The method of high-performance liquid chromatography with mass spectrometric detection was developed and validated for the quantitative determination of a new p...

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Bibliographic Details
Main Authors: P. O. Bochkov, I. P. Khrustova, A. A. Litvin, G. B. Kolyvanov, R. V. Shevchenko, V. P. Zherdev
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2022-01-01
Series:Фармакокинетика и Фармакодинамика
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Online Access:https://www.pharmacokinetica.ru/jour/article/view/281
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