VILIP3 attenuates neuronal apoptosis and oxidative stress via Nrf2 activation in the pathogenesis of Alzheimer’s disease

VILIP3 attenuates neuronal apoptosis and oxidative stress via Nrf2 activation in the pathogenesis of Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD) is a common neurodegenerative condition characterized by amyloid-β protein (Aβ) deposition, which is central to its pathological changes. Oxidative stress also plays an important role in its pathogenesis. Visinin-like protein 3 (VILIP3), a neuronal calciu...

Full description

Saved in:
Bibliographic Details
Main Authors: Shasha Huangfu, Xiaoyu Sang, Shiyue Zhou, Haixia Liu, Dongqing Cui, Yansheng Du, Xinyue Xing, Wenyan Liu, Jianzhong Bi, Zhaohong Xie
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Medicine
Subjects:
Alzheimer’s disease
VILIP3
Oxidative stress
Apoptosis
Nrf2
Neuroprotection
Online Access:https://doi.org/10.1186/s10020-025-01280-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s10020-025-01280-9

Similar Items