Identifying G-quadruplex-interacting proteins in cancer-related gene promoters

Abstract G-quadruplexes (G4s) are noncanonical DNA or RNA secondary structures involved in numerous biological processes. Their recognition by G4-related proteins (G4RPs) is essential for modulating biological pathways, particularly those associated with transcription and cancer progression. Identif...

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Bibliographic Details
Main Authors: Simona Marzano, Gabriella Pinto, Anna Di Porzio, Jussara Amato, Antonio Randazzo, Angela Amoresano, Bruno Pagano
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-025-01462-w
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