Quantification of oleanolic acid and apigenin in biological matrices following intraperitoneal administration of co-loaded nanoformulations: Method validation and biodistribution studies

Quantification of oleanolic acid and apigenin in biological matrices following intraperitoneal administration of co-loaded nanoformulations: Method validation and biodistribution studies

Oleanolic acid (OA) and apigenin (APG) demonstrate a wide range of pharmacological effects, including antioxidant, anti-inflammatory, antiviral, antidiabetic, hepatoprotective, and cardioprotective activities. Both compounds show anticancer potential and have been used individually to treat various...

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Bibliographic Details
Main Authors: Amna Naz, Sadia Haider, Mavra Rana, Neelum Malik, Attia Afzal, Muhammad Farooq, Muhammad Sarfraz
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Talanta Open
Subjects:
Oleanolic acid
Apigenin
Method validation
Simultaneous detection
Pharmacokinetic studies
Online Access:http://www.sciencedirect.com/science/article/pii/S2666831925000724
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