Inhibition of inflammatory cell infiltration by antagonistic peptides that specifically bind to CCR5 via regulation of the NF-kB signaling pathway in rats with colitis
Introduction CC chemokine receptor 5 (CCR5) and the NF-kB signaling pathway play important roles in the pathophysiology of inflammatory bowel disease (IBD). Previously, we synthesized two peptides (GH and HY peptides) that specifically bind to the first and the second extracellular loops (ECL1 and E...
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Main Authors: | Yang-Da Song, Yi-Hang Song, Si-Xue Liu, Hua-Rong Huang, Ying-Qiang Zhong |
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Format: | Article |
Language: | English |
Published: |
Termedia Publishing House
2021-05-01
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Series: | Archives of Medical Science |
Subjects: | |
Online Access: | https://www.archivesofmedicalscience.com/Inhibition-of-inflammatory-cell-infiltration-by-antagonistic-peptides-that-specifically,127587,0,2.html |
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