Inhibition of inflammatory cell infiltration by antagonistic peptides that specifically bind to CCR5 via regulation of the NF-kB signaling pathway in rats with colitis

Inhibition of inflammatory cell infiltration by antagonistic peptides that specifically bind to CCR5 via regulation of the NF-kB signaling pathway in rats with colitis

Introduction CC chemokine receptor 5 (CCR5) and the NF-kB signaling pathway play important roles in the pathophysiology of inflammatory bowel disease (IBD). Previously, we synthesized two peptides (GH and HY peptides) that specifically bind to the first and the second extracellular loops (ECL1 and E...

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Bibliographic Details
Main Authors: Yang-Da Song, Yi-Hang Song, Si-Xue Liu, Hua-Rong Huang, Ying-Qiang Zhong
Format: Article
Language:English
Published: Termedia Publishing House 2021-05-01
Series:Archives of Medical Science
Subjects:
inflammatory bowel disease
cc chemokine receptor 5
antagonistic peptides
nf-kb
Online Access:https://www.archivesofmedicalscience.com/Inhibition-of-inflammatory-cell-infiltration-by-antagonistic-peptides-that-specifically,127587,0,2.html
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