Cell-autonomous timing drives the vertebrate segmentation clock’s wave pattern

Cell-autonomous timing drives the vertebrate segmentation clock’s wave pattern

Rhythmic and sequential segmentation of the growing vertebrate body relies on the segmentation clock, a multi-cellular oscillating genetic network. The clock is visible as tissue-level kinematic waves of gene expression that travel through the presomitic mesoderm (PSM) and arrest at the position of...

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Bibliographic Details
Main Authors: Laurel A Rohde, Arianne Bercowsky-Rama, Guillaume Valentin, Sundar Ram Naganathan, Ravi A Desai, Petr Strnad, Daniele Soroldoni, Andrew C Oates
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
segmentation clock
zebrafish
somitogenesis
intrinsic timer
cell tracking
primary cell culture
Online Access:https://elifesciences.org/articles/93764
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https://elifesciences.org/articles/93764

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