An Obesity Risk SNP (rs17782313) near the MC4R Gene Is Associated with Cerebrocortical Insulin Resistance in Humans

Activation of melanocortin-4 receptor (MC4R) by insulin sensitive neurons is a central mechanism in body weight regulation, and genetic variants in the MC4R gene (e.g., rs17782313) are associated with obesity. By using magnetoencephalography, we addressed whether rs17782313 affects the cerebrocortic...

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Bibliographic Details
Main Authors: Otto Tschritter, Axel Haupt, Hubert Preissl, Caroline Ketterer, Anita M. Hennige, Tina Sartorius, Fausto Machicao, Andreas Fritsche, Hans-Ulrich Häring
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2011/283153
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