Polymer-free β-cyclodextrins and mefenamic acid inclusion complex nanofibers for enhanced drug solubility and biomedical applications

Polymer-free β-cyclodextrins and mefenamic acid inclusion complex nanofibers for enhanced drug solubility and biomedical applications

Abstract In this study, cyclodextrin (CDs) derivatives were used to form mefenamic acid (MFA) supramolecular inclusion complexes (ICs) via a polymer-free electrospinning technique, aiming to improve drug delivery and therapeutic applications. MFA, a non-steroidal anti-inflammatory drug (NSAID), has...

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Bibliographic Details
Main Authors: Sonaimuthu Mohandoss, Kuppu Sakthi Velu, Naushad Ahmad, Ramachandran Srinivasan, Prasanta Roy, Prathap Somu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Nanofibers
β-cyclodextrins
Solubility
Drug-release
Antibacterial, anticancer
Online Access:https://doi.org/10.1038/s41598-025-15651-z
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https://doi.org/10.1038/s41598-025-15651-z

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