Leptin receptor signaling mediates the distinct tendon–bone interface reconstruction in rotator cuff tears and osteoporosis-comorbid rotator cuff tears
Abstract Background The intact tendon–bone interface (TBI) consists of four histological layers—tendon, fibrocartilage, calcified fibrocartilage, and bone—that gradually merge into each other, making complete structural restoration after injury challenging. Osteoporosis poses a significant risk for...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | Stem Cell Research & Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13287-025-04586-x |
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