The Effect of Tacrine on Functional Response of the Lower Oesophageal Sphincter Assessed by Endoscopic Luminal Impedance Planimetry in Experimental Pigs

The Effect of Tacrine on Functional Response of the Lower Oesophageal Sphincter Assessed by Endoscopic Luminal Impedance Planimetry in Experimental Pigs

<b>Background/Objectives:</b> Tacrine is a centrally active non-competitive reversible acetylcholinesterase inhibitor. It also exerts antagonising activity against <i>N</i>-methyl-D-aspartate receptors. Tacrine was approved for the treatment of Alzheimer’s disease in 1993, bu...

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Main Authors: Jan Bures, Martin Novak, Vera Radochova, Darina Kohoutova, Lukas Prchal, Jan Martinek, Jan Mares, Jaroslav Cerny, Stepan Suchanek, Jaroslav Pejchal, Barbora Voxova, Petr Urbanek, Miroslav Zavoral, Ondrej Soukup
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
Alzheimer’s disease
endoscopic luminal impedance planimetry
experimental pigs
lower oesophageal sphincter
tacrine
Online Access:https://www.mdpi.com/1424-8247/17/12/1588
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