Caffeic acid phenethyl ester protects renal tubular epithelial cells against ferroptosis in diabetic kidney disease via restoring PINK1-mediated mitophagy

Abstract Mounting evidence indicates that renal tubular ferroptosis plays a crucial role in the progression of diabetic kidney disease (DKD). Caffeic acid phenethyl ester (CAPE), derived from propolis, a precious resinous substance synthesized by various bee species, has garnered broad attention in...

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Bibliographic Details
Main Authors: Ying Lu, Ye Zhu, Sheng Feng, Qifei Cong, Sixia Chen, Ying Zeng, Kai Song, Ji Hu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-025-01318-y
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