ROS-responsive drug delivery system with enhanced anti-angiogenic and anti-inflammatory properties for neovascular age-related macular degeneration therapy

ROS-responsive drug delivery system with enhanced anti-angiogenic and anti-inflammatory properties for neovascular age-related macular degeneration therapy

Neovascular age-related macular degeneration (nAMD) has become the leading cause of vision loss in people over 60 years old. Anti–vascular endothelial growth factor (anti-VEGF), the current first-line drug for the treatment of nAMD, suffers from poor patient compliance and fundus fibrosis scar forma...

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Bibliographic Details
Main Authors: Jiayi Zuo, Yining Pan, Yuanli Wang, Wei Wang, Haojie Zhang, Si Zhang, Youru Wu, Jiangfan Chen, Qingqing Yao
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Subjects:
Age-related macular degeneration
Integrated nano-drug delivery system
Yes-associated protein-1
Anti-angiogenic
ROS-Scavenging
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425003175
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