Role of layilin in regulating mitochondria-mediated apoptosis: a study on B cell lymphoma (BCL)-2 family proteins

Abstract Background Malignant gliomas exhibit rapid tumor progression and resistance to treatment, leading to high lethality. One of the causes is the reduced progression of apoptosis in glioma cells. Layilin is a type 1 transmembrane protein with a C-type lectin motif in its extracellular domain. W...

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Main Authors: Mitsumi Arito, Atsuhiro Tsutiya, Masaaki Sato, Kazuki Omoteyama, Toshiyuki Sato, Yusei Motonaga, Naoya Suematsu, Manae S. Kurokawa, Tomohiro Kato
Format: Article
Language:English
Published: BMC 2024-10-01
Series:BMC Molecular and Cell Biology
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Online Access:https://doi.org/10.1186/s12860-024-00521-9
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