Nintedanib regulates miR-23b-3p/TGFBR2 axis and competitively binds to TGFBR2 protein, inhibiting EMT process in human pterygium cells

AIM: To investigate the effects of nintedanib on epithelial-mesenchymal transition (EMT) in cells derived from pterygium, aiming to explore its potential as a pharmacological intervention for pterygium treatment. METHODS: Primary human pterygium epithelial cells (hPEC) and human conjunctival epithel...

Full description

Saved in:
Bibliographic Details
Main Authors: Ke-Ke Zhang, Meng Li, Yan-Hong Liao, Xiao-Tian Liu, Yong-Bo Bao, Yan Gong
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2025-05-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://ies.ijo.cn/en_publish/2025/5/20250503.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!