Streptococcus mutans-derived extracellular vesicles promote skin wound healing via tRNA cargo

Streptococcus mutans-derived extracellular vesicles promote skin wound healing via tRNA cargo

Abstract Background The human oral cavity harbors a diverse microbiota, including Streptococcus species. Oral mucosal wounds heal rapidly, although the exact cause remains unclear. This study investigates the impact of Streptococcus mutans-derived extracellular vesicles (Sm EVs) on wound healing in...

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Main Authors: Su Young Oh, Dong Yeon Kim, Kah Young Lee, Dae-Lyong Ha, Tae-Lyn Kim, Tae-Geon Kwon, Jin-Wook Kim, Heon-Jin Lee, So-Young Choi, Su-Hyung Hong
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Nanobiotechnology
Subjects:
Streptococcus mutans
Extracellular vesicles
Oral mucosa
Skin wound healing
TLR3
Bacterial tRNA
Online Access:https://doi.org/10.1186/s12951-025-03410-1
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https://doi.org/10.1186/s12951-025-03410-1

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