IL-33/ST2 axis mediates diesel exhaust particles-induced mast cell activation

Abstract Background Mast cells are implicated in the pathogenesis and severity of asthma in children and adults. The release of proinflammatory mediators and cytokines from activated mast cells (MC) is associated with Type 2 (T2) cell-skewed inflammation. Methods We obtained the airway tissues of Ba...

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Bibliographic Details
Main Authors: Wun-Hao Cheng, Ting-Li Zhuang, Meng-Jung Lee, Chun-Liang Chou, Bing-Chang Chen, Han-Pin Kuo, Chih-Ming Weng
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-024-01035-y
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