CRISPR/Cas9 a genomic engineering technology for treatment in ALS mouse models
Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disorder characterized by the death of motor neurons in the spinal cord and brain regions, leading to a reduced survival rate in patients. Nearly 20 gene mutations are associated with ALS, with SOD1, FUS, TARDBP, and C9orf72 mutation...
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| Main Authors: | Hamid Khan, Hammad Riaz, Adeel Ahmed, Mubin Mustafa Kiyani, Sahibzada Muhammad Jawad, Syed Shahab Ud Din Shah, Turki Abualait, Fawaz Al-hussain, Hong-Tao Li, Shahid Bashir |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-12-01
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| Series: | Regenerative Therapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352320425001634 |
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