Disruption of sulfur transferase complex increases bacterial intramacrophage persistence.

Disruption of sulfur transferase complex increases bacterial intramacrophage persistence.

Bacterial persisters contribute significantly to clinical treatment failure and relapse. These cells could resist antibiotic treatment via transient phenotypic and gene expression alterations. We conducted a high-throughput screening of Salmonella Typhimurium transposon mutants to identify key genes...

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Main Authors: Huang Tang, Zuoqiang Wang, Congcong Li, Jingchen Yu, Wanqiu Huang, Tao Zhou, Chuanzhen Zhang, Bingjie Wen, Chengyue Wang, Xiaocen Zhu, Danni Wang, Jing Tao, Jie Lu, Jinjing Ni, Yu-Feng Yao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013136
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https://doi.org/10.1371/journal.ppat.1013136

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