Dissecting the genetic determinants and biological associations between body mass index and female reproductive disorders based on genome-wide association study

Dissecting the genetic determinants and biological associations between body mass index and female reproductive disorders based on genome-wide association study

Abstract Background While the phenotypic link between body mass index (BMI) and some female reproductive disorders is well established, the genetic architecture and causal relationships have not been systematically studied. We aimed to create an atlas of the shared genetic associations of BMI and 16...

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Main Authors: Huijing Shao, Chang Xu, Haoran Wang, Nan Lu, Hang Gu, Caihong Zhang, Lirong Li, Qianqian Sun, Rui Guan, Beibei Xuan
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Reproductive Biology and Endocrinology
Subjects:
Body mass index
Female reproductive disorders
Genetic architecture
Hormones
Metabolites
Online Access:https://doi.org/10.1186/s12958-025-01406-y
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https://doi.org/10.1186/s12958-025-01406-y

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