MRPL13 enhances mitochondrial function and promotes tumor progression in ovarian cancer by inhibiting mPTP opening via SLC25A6

Abstract Tumor cells typically exhibit dysregulation of mitochondrial energy metabolism and cell death. The role of mitochondrial function in ovarian cancer (OC) progression has garnered substantial attention, yet its precise molecular mechanisms remain elusive. Mitochondrial ribosomal protein L13 (...

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Bibliographic Details
Main Authors: Ouxuan Liu, Yuexin Hu, Shuang Wang, Xin Nie, Yuxuan Wang, Xiangcheng Fan, Kai Zeng, Xiao Li, Bingying Liu, Bei Lin
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07953-x
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