Biomimetic phosphorus dendrimer multi-epitope nanovaccine enhances humoral and cellular immune response against African swine fever virus

Biomimetic phosphorus dendrimer multi-epitope nanovaccine enhances humoral and cellular immune response against African swine fever virus

Abstract Using nanoparticles (NPs) as a platform for multivalent antigen display is an effective strategy to increase the immunogenicity of subunit vaccines, which can induce high levels of humoral and cellular immunity. In addition, antigens that target antigen-presenting cells (APCs) can further i...

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Bibliographic Details
Main Authors: Hong Duan, Aijuan Shen, Min Wang, Fengxia Zhang, Ziheng Zhang, Yaci Zhang, Yunshuo Lu, Qiming Pei, Angke Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Nanobiotechnology
Subjects:
African swine fever
Multiepitope nanovaccine
B-cell response
T-cell response
Online Access:https://doi.org/10.1186/s12951-025-03593-7
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https://doi.org/10.1186/s12951-025-03593-7

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