Multi-omics dissection of metabolic dysregulation associated with immune recovery in people living with HIV-1

Multi-omics dissection of metabolic dysregulation associated with immune recovery in people living with HIV-1

Abstract Background Despite the success of antiretroviral therapy (ART) in suppressing HIV-1 replication, some people living with HIV-1 (PLWH) fail to achieve an optimal recovery of CD4 T cells, and precise metabolic regulation underlying immune recovery remained poorly understood. Methods In this c...

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Main Authors: Lin-Yu Wan, Sin Man Lam, Hui-Huang Huang, Wen-Jing Cao, Xiang-Yi Cao, Xue-Meng Li, Li-Ping Zhang, Jia-Min Gao, Chao Zhang, Xing Fan, Yan-Mei Jiao, Guanghou Shui, Fu-Sheng Wang, Jin-Wen Song
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
HIV-1
Immune recovery
Metabolome
Lipidome
Online Access:https://doi.org/10.1186/s12967-025-06168-0
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https://doi.org/10.1186/s12967-025-06168-0

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