Prediction of deep remission through serum TNF-α level at 1 year of treatment in pediatric Crohn’s disease

Prediction of deep remission through serum TNF-α level at 1 year of treatment in pediatric Crohn’s disease

Abstract A pilot study investigated the cytokine profile (IL-6, TNF-α, IL-17 A, and IL-10) at diagnosis, affecting infliximab (IFX) trough levels (TLs) in pediatric patients with Crohn’s disease (CD). In this follow-up study, we evaluated the changes in cytokine level changes after Crohn’s disease t...

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Bibliographic Details
Main Authors: Seon Young Kim, Yiyoung Kwon, Eun Sil Kim, Yoon Zi Kim, Hansol Kim, Yon Ho Choe, Mi Jin Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Crohn’s disease
TNF-α
Infliximab
Cytokines
Online Access:https://doi.org/10.1038/s41598-025-89578-w
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https://doi.org/10.1038/s41598-025-89578-w

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