Nanoplastics aggravate severe asthma by inducing DNA damage of alveolar type Ⅱ epithelial cells

Objective·To explore the effects and possible molecular mechanisms of nanoplastics (NPs) on severe asthma.Methods·A mouse model of severe asthma was established by using house dust mite (HDM) and lipopolysaccharide (LPS) co-stimulation. Polystyrene nanoplastics (PS-NPs) were instilled into the sever...

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Bibliographic Details
Main Authors: SHI Zelun, WANG Qing, HE Wen, FU Weijia, WANG Yingwen, HAN Xiao, ZHANG Xiaobo
Format: Article
Language:zho
Published: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2024-11-01
Series:Shanghai Jiaotong Daxue xuebao. Yixue ban
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Online Access:https://xuebao.shsmu.edu.cn/article/2024/1674-8115/1674-8115-2024-44-11-1391.shtml
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