Low-dose ATG/PTCy for graft-versus-host disease prevention in haploidentical transplantation: a single-center experience

Low-dose ATG/PTCy for graft-versus-host disease prevention in haploidentical transplantation: a single-center experience

BackgroundThe combination of anti-thymocyte globulin (ATG) and post-transplant cyclophosphamide (PTCy) has been administered for graft-versus-host disease (GVHD) prophylaxis of haploidentical hematopoietic stem cell transplantation (haplo-HSCT) in recent years. Varied doses of ATG and PTCy were appl...

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Main Authors: Jian Hong, Xinglin Liang, Jing Ni, Min Ruan, Zhangbiao Long, Jifei Dai, Li Liang, Mingya Yang, Ziyang Zhang, Shihao Zhang, Jian Ge, Mingzhen Yang, Qingsheng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
Subjects:
anti-thymocyte globulin
post-transplant cyclophosphamide
graft-versus-host disease
haploidentical hematopoietic stem cell transplantation
absolute lymphocyte count
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1569149/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1569149/full

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