Single-Cell Profiling of Tubular Epithelial Cells in Adaptive State in the Urine Sediment of Patients With Early and Advanced Diabetic Kidney Disease

Single-Cell Profiling of Tubular Epithelial Cells in Adaptive State in the Urine Sediment of Patients With Early and Advanced Diabetic Kidney Disease

Introduction: Tubular epithelial cells (TECs) under adaptive state (aTECs) have been frequently reported in the injured kidney closely associated with disease progression. However, whether aTECs is present in the urine of patients with diabetic kidney disease (DKD) and its clinical implication have...

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Bibliographic Details
Main Authors: Dongzhao Ma, Dan Wang, Jianwen Yu, Naya Huang, Ning Luo, Yue Yang, Minghui Xu, Jianbo Li, Yagui Qiu, Jinjin Fan, Zhijian Li, Wei Chen, Qin Zhou
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Kidney International Reports
Subjects:
adaptive state
DKD
scRNA-seq
tubular epithelial cells
tubular injury
urine
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024924020114
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